Posts Tagged ‘myeloma’

60-Year-Old Man with Bone Pain

Posted by • October 24th, 2014

In the latest Case Record of the Massachusetts General Hospital, a 60-year-old man was seen in the outpatient cancer center because of bone pain that had lasted for 2 months and the presence of lytic bone lesions on imaging studies. Biopsy specimens of bone marrow and bone lesions showed increased mast cells. A diagnostic procedure… Read More…


Posted by • September 23rd, 2011

In the latest Case Record of the Massachusetts General Hospital, cardiac and renal failure developed in a 66-year-old woman. Echocardiography suggested infiltrative cardiomyopathy, lytic bone lesions were seen on imaging, and elevated serum free light chains were detected. A diagnostic procedure was performed.                 Categories of plasma-cell neoplasms include monoclonal gammopathy of unknown significance (MGUS), asymptomatic plasma-cell… Read More…

Multiple Myeloma

Posted by • March 18th, 2011

The latest article in our Medical Progress series, Multiple Myeloma, comes from Dr. Antonio Palumbo at the University of Turin, and Dr. Kenneth Anderson at Harvard Medical School and Dana-Farber Cancer Institute. Multiple myeloma is a neoplastic plasma cell disorder characterized by clonal proliferation of malignant plasma cells in the bone marrow microenvironment, monoclonal protein in… Read More…