Posts Tagged ‘polymyositis’

Eye of the Beholder

Posted by • May 6th, 2016

Dermatomyositis, polymyositis, and necrotizing autoimmune myopathy all cause proximal muscle weakness. Proximal weakness is often progressive, with patients reporting difficulty in raising their arms above their head, climbing stairs, or standing from a seated position. Clinically, dermatomyositis is distinguished from polymyositis and necrotizing autoimmune myopathy by its distinctive dermal findings. A 47-year-old man presented to an… Read More…

Inflammatory Muscle Diseases

Posted by • May 1st, 2015

The four main types of inflammatory muscle disease — dermatomyositis, polymyositis, necrotizing autoimmune myositis, and inclusion-body myositis — are summarized in a new review article. Pathogenesis, differential diagnosis, and treatment approaches are discussed. The inflammatory myopathies constitute a heterogeneous group of disorders that are best classified, on the basis of distinct clinicopathologic features, as four subtypes:… Read More…

A 34-Year-Old Woman with Increasing Dyspnea

Posted by • March 21st, 2014

In the latest Case Record of the Massachusetts General Hospital, a 34-year-old woman with a history of Raynaud’s phenomenon and symmetric joint pain was admitted to the hospital because of increasing dyspnea. An echocardiogram showed severe pulmonary hypertension. Diagnostic test results were received. A diagnosis of pulmonary hypertension can be confirmed in a straightforward manner by… Read More…

Muscle Pain and Swelling

Posted by • August 23rd, 2013

In the latest Case Record of the Massachusetts General Hospital, a 46-year-old woman presented with pain and swelling in her arms and lower legs for 3 weeks. Examination showed swelling and tenderness of the left arm and tenderness in both calves. Chest imaging revealed a mediastinal mass. A diagnostic procedure was performed. Central immune tolerance is… Read More…