Posts Tagged ‘scleroderma’

Raynaud’s Phenomenon

Posted by • August 11th, 2016

Although laboratory testing provides important information about the hemodynamic and physiological features of Raynaud’s phenomenon, clinical assessment by means of history or direct observation remains the best approach for diagnosis. Most experts agree that at least biphasic (white [pallor] and blue [cyanosis]) change in the skin color of the digits is needed. A new Review… Read More…

A 34-Year-Old Woman with Increasing Dyspnea

Posted by • March 21st, 2014

In the latest Case Record of the Massachusetts General Hospital, a 34-year-old woman with a history of Raynaud’s phenomenon and symmetric joint pain was admitted to the hospital because of increasing dyspnea. An echocardiogram showed severe pulmonary hypertension. Diagnostic test results were received. A diagnosis of pulmonary hypertension can be confirmed in a straightforward manner by… Read More…

Scleroderma Renal Crisis

Posted by • September 30th, 2011

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old woman with autoimmune overlap syndrome and polymyositis presented with anemia, thrombocytopenia, and acute renal failure. Four days before admission, she was found on the floor of her home, confused and minimally conversant.                                Approximately 70% of patients with diffuse cutaneous systemic sclerosis have kidney involvement, even… Read More…