Posts Tagged ‘SLE’

A 34-Year-Old Woman with Increasing Dyspnea

Posted by • March 21st, 2014

In the latest Case Record of the Massachusetts General Hospital, a 34-year-old woman with a history of Raynaud’s phenomenon and symmetric joint pain was admitted to the hospital because of increasing dyspnea. An echocardiogram showed severe pulmonary hypertension. Diagnostic test results were received. A diagnosis of pulmonary hypertension can be confirmed in a straightforward manner by… Read More…

Belimumab for SLE

Posted by • April 19th, 2013

In the latest review article in our Clinical Therapeutics series, a 20-year-old woman with SLE presents with disease flares and receives belimumab, a monoclonal antibody that binds to B-cell activating factor, inhibiting B-cell stimulation. Belimumab is considered for patients who do not have a response or have adverse effects with first-line therapies. Clinical Pearls • What… Read More…

Wolf at the Door

Posted by • June 8th, 2012

In the latest Clinical Problem-Solving article, a 29-year-old man presented with a 1-week history of fever, night sweats, reduced appetite, and left upper abdominal pain exacerbated by inspiration. He reported no weight loss, cough, dyspnea, nausea, diarrhea, rash, mouth ulcers, arthralgias, or ocular or urinary symptoms. Systemic lupus erythematosus (SLE) and the hemophagocytic syndrome are two… Read More…