Posts Tagged ‘statin’

Primary Prevention of Cardiovascular Events — A Pragmatic Approach

Posted by • May 25th, 2016

Ms. Barnstable is a 66 year-old woman who is seeing you for an annual physical check-up today.  She does not take any medications and is a smoker.  She asks if there are drugs that she should be taking to lower her risks for heart attacks and strokes. Besides smoking cessation counseling, what do you tell… Read More…

Statin-Associated Autoimmune Myopathy

Posted by • February 19th, 2016

Statins significantly reduce the incidence of cardiovascular disease, are generally safe, and have an acceptable side-effect profile. It is now recognized, however, that in very rare cases, an autoimmune myopathy develops in patients treated with statins; this disorder is characterized by muscle weakness, evidence of muscle-cell necrosis on biopsy, and the presence of autoantibodies against… Read More…

Ezetimibe and Cardiovascular Outcomes

Posted by • June 3rd, 2015

As you walk into Mr. R’s room to see if he has last-minute questions about his discharge medications, you can’t believe how different – how much better – he looks dressed in his usual clothes, instead of an errantly-snapped hospital gown.   You met him 4 days ago, when he was wheeled, pale and groggy, onto… Read More…

New Clinical Decisions: The Guidelines Battle on Starting Statins

Posted by • April 24th, 2014

Stephen, a 52-year-old white jogger with a body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) of 25, wants you to assess his cardiovascular risks. He had scheduled his visit after taking his father to another physician to discuss his father’s blindness, which is related to type 2… Read More…

Statins and Atherosclerosis

Posted by • December 2nd, 2011

In the SATURN trial, intravascular ultrasonography was used to compare the effects of atorvastatin versus rosuvastatin on regression of coronary atherosclerosis. Both statins led to regression in two thirds of patients, with no significant difference between their effects. Statins reduce adverse cardiovascular outcomes and slow the progression of coronary atherosclerosis in proportion to their ability to… Read More…