Posts Tagged ‘TB’

Less is not more for TB treatment

Posted by • October 22nd, 2014

Shorter regimens fail to be non-inferior to the standard tuberculosis treatment plans One third of the world’s population is currently infected with tuberculosis (TB), and, in 2012, there were 1.3 million TB-related deaths (Centers for Disease Control and Prevention). Moreover, in 2012, 450,000 people worldwide developed multi-drug resistant TB (MDR TB), which is resistant to at… Read More…

Tuberculosis Control in the Gold Mines of South Africa

Posted by • January 22nd, 2014

It’s a clinical trialist’s dream: A prevalent disease, an effective intervention, and an implementation strategy that’s practical in a community setting. How could the result be anything but dramatically positive? In this week’s NEJM, the Thibela TB study investigators report on a cluster-randomized trial with a setting precisely this promising – and discuss their unexpected results…. Read More…

Chronic Infectious Disease and the Future of Health Care Delivery

Posted by • December 20th, 2013

Work that has been done in low-income countries to build health systems that can respond to AIDS and TB (as well as other acute and chronic diseases) shows that with adequate resources, we can improve care delivery, sharply reducing morbidity and mortality.  This week’s new Shattuck Lecture discusses lessons from 25 years of responding to… Read More…