Posts Tagged ‘ulcerative colitis’

37-Year-Old Man with Ulcerative Colitis and Bloody Diarrhea

Posted by • August 15th, 2014

In the latest Case Record of the Massachusetts General Hospital, a 37-year-old man with ulcerative colitis was admitted to the hospital because of abdominal cramping, diarrhea, hematochezia, fever to a peak temperature of 38.8°C, and drenching night sweats. Several weeks earlier, he had performed home fecal transplantation. Bloody diarrhea is characteristic of infections caused by Escherichia… Read More…

TNF Inhibitors for Inflammatory Bowel Disease

Posted by • August 23rd, 2013

In the latest review article in our Clinical Therapeutics series, a 35-year-old man presents with an exacerbation of Crohn’s disease. Treatment with a TNF inhibitor is recommended. TNF inhibitors block the effects of the proinflammatory cytokine TNF-α, and several have been shown to be effective in treating inflammatory bowel disease. Inflammatory bowel disease, an umbrella term… Read More…

Vedolizumab Therapy for Ulcerative Colitis and Crohn’s Disease

Posted by • August 21st, 2013

A friend of mine, who has spent 15 years dealing with the ebbs and flows of ulcerative colitis (UC), is the kind of patient who would hope her physician pays attention to the results of two RCTs published this week in NEJM. She is one of an estimated 1.4 million Americans diagnosed with UC or… Read More…

Complex Cause of Pleuritic Chest Pain

Posted by • November 2nd, 2012

In the latest article in our Clinical Problem-Solving series, a 33-year-old man presented to the emergency department with pain in the right side of his chest. The pain had started 5 days earlier and was worse with deep inspiration and recumbency. He also noted mild swelling of his lower legs over the preceding several weeks. Ulcerative… Read More…

Ulcerative Colitis

Posted by • November 4th, 2011

Ulcerative colitis is the most common form of inflammatory bowel disease. Its course is often mild, with few complications, and it can be cured by colectomy. Our current understanding of its pathophysiology, diagnosis, and treatment is reviewed in a new Medical Progress article. Ulcerative colitis is the most common form of inflammatory bowel disease worldwide. In… Read More…