Our popular Clinical Decisions feature centers on what you would do in a given clinical setting and why. The latest in this series presented the fictional case of a 56-year-old homeless man found to have a subarachnoid hemorrhage and acute hydrocephalus. He was in a coma, and his prognosis, at best, was to be left with severe dependent disability. We asked you to consider three options for a patient who was unable to speak for himself. Visit NEJM.org to see how your peers voted, and to access earlier Clinical Decisions on the management of skin and soft-tissue infection, Type 2 diabetes, stable coronary disease, and the treatment of mild persistent asthma.