Posts Tagged ‘HIV’

Adjunctive Steroids and Harm in Cryptococcal Meningitis

Posted by • February 10th, 2016

In the recent best-selling book and award-nominated movie, The Martian, astronaut and botanist Mark Watney is stranded alone on Mars.  The story follows his attempts to defy certain death and, through creativity and scientific experimentation, use his limited resources to generate oxygen, grow food, and make it home to Earth.  Recently the medical community has… Read More…

Amoxicillin for Severe Acute Malnutrition

Posted by • February 5th, 2016

Severe acute malnutrition affects approximately 19 million children under 5 years of age worldwide and contributes substantially to mortality and the disease burden among children. Only one previous randomized trial has examined the routine use of antibiotics in the community-based treatment of severe acute malnutrition. Isanaka et al. conducted a randomized, double-blind, placebo-controlled trial in… Read More…

Men Who Have Sex with Men

Posted by • August 28th, 2015

A new Clinical Practice article covers primary care for men who have sex with men. Care should include a detailed sexual history to assess the risk of infection with HIV, the use of preexposure prophylaxis for those at high risk, and appropriate vaccinations and regular testing for sexually transmitted infections. Men who have sex with men,… Read More…

Preexposure Prophylaxis for HIV-1 Infection

Posted by • February 4th, 2015

In December 2007, Elizabeth Mataka, the United Nations Special Envoy for HIV/AIDS in Africa, highlighted one of many stark realities of the HIV epidemic: “61% of all those living with HIV in Africa are women,” she wrote. “And 26 years into the epidemic, we know that underpinning this terrible statistic is gender inequality.” Condoms work. But… Read More…

Influenza Vaccination in Pregnancy

Posted by • September 3rd, 2014

As the days get shorter and cooler, you have an increasing sense of dread that Winter Is Coming – and with it comes flu season.   Once you stop daydreaming of the halcyon days of summer, you notice that in your waiting room are two pregnant patients, one HIV positive, one HIV negative. You take a moment… Read More…

46-Year-Old Woman in Botswana with Postcoital Bleeding

Posted by • May 23rd, 2014

In the latest Case Record of the Massachusetts General Hospital, a 46-year-old woman with HIV and a high-grade squamous intraepithelial lesion was evaluated in Botswana because of postcoital bleeding. During examination of the cervix and vagina, a large fungating lesion was seen. Diagnostic procedures were performed. Postcoital bleeding is defined as bleeding that occurs during or… Read More…

29-Year-Old Man with Headache and Diplopia

Posted by • March 14th, 2014

In the latest Case Record of the Massachusetts General Hospital, a 29-year-old man was admitted to the hospital because of headache, vomiting, photophobia, diplopia, and stiff neck. He was born in Southeast Asia. Brain imaging showed diffuse leptomeningeal enhancement. Cultures were sterile. A diagnostic procedure was performed. Chronic meningitis differs in important ways from acute meningitis…. Read More…

Malaise and Chest and Abdominal Pain

Posted by • November 29th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 41-year-old woman with a history of HIV infection was admitted to the hospital because of malaise and chest and abdominal pain. Initial laboratory evaluation was notable for elevated hepatic aminotransferase levels. Diagnostic procedures were performed. Hepatic injury with significant elevations in transaminases has been reported… Read More…

Abdominal Pain, Fever, and Weight Loss

Posted by • October 11th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 29-year-old man was seen in an outpatient clinic because of abdominal pain, fever, and weight loss. Testing for HIV antibodies was positive, and the CD4 T-lymphocyte count was 10 per cubic millimeter. Chest imaging revealed tiny nodules in both lungs. This case illustrates the importance… Read More…

The AIDS Pandemic

Posted by • June 7th, 2013

The HIV–AIDS pandemic is now in its fourth decade. The latest article in our new Global Health series describes how HIV–AIDS has been transformed from a death sentence into a manageable illness and outlines the need for continued and coordinated international efforts. It was not until the third decade of the epidemic that the world’s public… Read More…