Posts Tagged ‘renal replacement therapy’

Initiation Strategies for Renal-Replacement Therapy

Posted by • July 14th, 2016

Renal-replacement therapy is the cornerstone of the management of severe acute kidney injury. Gaudry et al. compared a strategy of early initiation of renal-replacement therapy with a strategy of delayed initiation in patients in the intensive care unit who had acute kidney injury of Kidney Disease: Improving Global Outcomes (KDIGO) classification stage 3. This multicenter randomized… Read More…

Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit

Posted by • July 6th, 2016

Ms. G is a 42-year-old woman admitted to your ICU with septic shock in the setting of a urinary tract infection.  She was started on a norepinephrine infusion in the emergency room. Her labs reveal a creatinine of 3.0 mg/dL, increased from a prior baseline of 0.6 mg/dL; pH is 7.3 and potassium is 4.9… Read More…

Continuous Renal-Replacement Therapy

Posted by • December 28th, 2012

In the latest review article in our Clinical Therapeutics series, a 20-year-old man with Marfan’s syndrome develops acute kidney injury after an aortic-valve replacement that was complicated by thoracic aortic dissection. Continuous renal-replacement therapy, rather than intermittent hemodialysis, is recommended because of hemodynamic instability. Acute kidney injury is characterized by a sudden decrease in kidney function… Read More…

Chronic Dialysis: Now or Later?

Posted by • June 28th, 2010

The optimal timing for the initiation of dialysis among patients with Stage V chronic kidney disease (CKD) has been controversial. Some observational and case-controlled studies have suggested that starting dialysis when the estimated glomerular filtration rate (eGFR) is above 10 mL/min/1.73m2 (“early-start” dialysis) may improve patient survival and reduce morbidity compared to starting at an… Read More…