Posts Tagged ‘vitamin B12 deficiency’

Vitamin B12 Deficiency

Posted by Sara Fazio • January 11th, 2013

Vitamin B12 deficiency causes reversible megaloblastic anemia, demyelinating disease, or both. Current assays have insufficient sensitivity and specificity; methylmalonic acid levels are useful to confirm diagnosis. Parenteral or highdose oral vitamin B12 is effective therapy.  The latest article in our Clinical Practice series, Vitamin B12 Deficiency, comes from Dr. Sally P. Stabler at the University… Read More…

Paresthesias and Anemia

Posted by Sara Fazio • April 25th, 2012

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old man was admitted to this hospital because of paresthesias, weight loss, jaundice, and anemia. Diagnostic test results were received. Paresthesias involve a sensation of tingling, numbness, crawling, or deadness, and they are felt mainly in distal parts of the extremities. Although they very rarely involve… Read More…