Larry Husten, PHD
November 11th, 2009
CRT May Reverse Remodeling in Heart Failure with Mild Symptoms
Larry Husten, PHD
In the REVERSE trial, 610 patients with NYHA I/II heart failure were randomized to active versus no CRT. At 12 months, active CRT was associated with reduced LV dimensions and increased EF in cases of non-ischemic cardiomyopathy.
November 4th, 2009
Aspirin for Primary Prevention ‘Should Not Be Routinely Initiated’
Larry Husten, PHD
Aspirin “should not be routinely initiated” for the primary prevention of cardiovascular disease, and for patients already taking aspirin, its use should be reviewed, advises the BMJ publication Drug and Therapeutics Bulletin. After considering the recommendations of several meta-analyses, the authors conclude that the available evidence “does not justify the routine use of low-dose aspirin […]
October 31st, 2009
2009 ACCF/AHA Guidelines More Conservative on Perioperative Beta-Blockade
Larry Husten, PHD
The ACCF/AHA have released a focused guidelines update that takes a more conservative stance on perioperative use of beta-blockade in patients undergoing noncardiac and vascular surgery.
NEJM — Recent Cardiology Articles- Seeing the Left Main Coronary Artery Clearly — Is IVUS Always Necessary? June 11, 2026Treatment of the left main coronary artery with percutaneous coronary intervention (PCI) in the absence of previous surgical revascularization, also referred to as an unprotected left main coronary artery PCI, is one of the riskier tasks that interventional cardiologists are asked to perform. Stent implantation in the left main coronary...
- IVUS — A Zigzag Path to Success June 11, 2026The use of intravascular ultrasound (IVUS) imaging for assessment of the coronary arteries has an almost 40-year history. In an editorial comment on an early ex vivo assessment of the accuracy of IVUS in evaluating human coronary arteries, Yock and Linker1 posed three questions that remain relevant today:...
- Prescription without Precision — Dangers of Dosing on the Basis of Race as Biology June 11, 2026Despite recognition that racial and ethnic categories are poor proxies for genetic diversity, race is still used to guide pharmaceutical use, posing risks of ineffectively low or dangerously high dosing.
- Case 16-2026: A 14-Year-Old Girl with Hypertension June 11, 2026A 14-year-old girl was admitted to the hospital because of hypertension and headache. She had hypokalemia, an elevated blood level of C-reactive protein, and an elevated erythrocyte sedimentation rate. A diagnosis was made.
- Antidotes for Anticoagulation Reversal June 11, 2026The authors review current strategies for anticoagulation reversal in major bleeding events or urgent surgery as well as specific antidotes, limits of available evidence, thrombotic risks, unmet therapeutic needs, and ongoing research.
- Seeing the Left Main Coronary Artery Clearly — Is IVUS Always Necessary? June 11, 2026