An ongoing dialogue on HIV/AIDS, infectious diseases,
Paul E. Sax, MD
Associate Editor
NEJM Clinician
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FROM NEJM — Recent Infectious Disease Articles- A Zoonotic Orthonairovirus from Febrile Patients in China September 3, 2026A new pathogenic orthonairovirus was identified in patients with a febrile illness in China. This virus was found in Haemaphysalis longicornis ticks in the same region.
- Pulmonary Nodules September 3, 2026This review summarizes the management of pulmonary nodules, with an emphasis on nodule type, imaging follow-up, cancer risk, and strategies to balance timely diagnosis with avoidance of unnecessary procedures.
- Fluid Resuscitation in Patients with Sepsis — For Whom the Balance Tolls September 3, 2026Improving the clinical treatment of patients with sepsis remains a major focus of critical care physicians worldwide.1,2 To date, few studies in either the pediatric or adult literature have established universal management principles that reliably improve outcomes, which attests to the heterogeneity of this syndrome. Fluid resuscitation is...
- Scrofuloderma September 3, 2026A 72-year-old man presented with a 2-month history of a painful lump on his neck. Cytologic analysis of fine-needle aspirate was consistent with suppurative lymphadenopathy. The lesion subsequently ulcerated and released purulent discharge.
- Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock September 3, 2026In children with septic shock, no significant difference was seen in the incidence of death, new renal-replacement therapy, or persistent kidney dysfunction with balanced fluid as compared with 0.9% saline for fluid resuscitation.
- A Zoonotic Orthonairovirus from Febrile Patients in China September 3, 2026