Posts Tagged ‘Disorders of Fluids and Electrolytes’

Vasopressin Antagonists

Posted by • June 5th, 2015

A new review in the Disorders of Fluids and Electrolytes series summarizes the salient discoveries that culminated in the development of vasopressin antagonists, focusing on their actions, side effects, emerging safety concerns, and important gaps in data. The review also considers how and when to use these agents. Ample evidence is available to implicate vasopressin, a… Read More…

Take the Fluids and Electrolytes Challenge

Posted by • March 23rd, 2015

A 53-year-old woman with chronic kidney disease, hypertension, and a mood disorder presented with irritability and pressured speech. Lab data include: blood pressure 130/85 mm Hg, plasma sodium 155 mmol/L, potassium 4.5 mmol/L, blood urea nitrogen 67 mg/dL, creatinine 1.99 mg/dL, glucose 90 mg/dL, and plasma osmolality 339 mOsm/L. What is the best strategy to… Read More…

Disorders of Plasma Sodium

Posted by • January 2nd, 2015

The latest review in the Disorders of Fluids and Electrolytes series considers the causes and consequences of an abnormal plasma sodium concentration and offers a framework for correcting it. Human cells dwell in salt water. Their well-being depends on the ability of the body to regulate the salinity of extracellular fluids. By controlling water intake and… Read More…

Acid-Base Disturbances

Posted by • October 10th, 2014

Acid–base homeostasis is fundamental for maintaining life. The first article in the new Disorders of Fluids and Electrolytes series reviews a stepwise method for the physiological approach to evaluation of acid–base status. Internal acid-base homeostasis is fundamental for maintaining life. Accurate and timely interpretation of an acid-base disorder can be lifesaving, but establishment of a correct… Read More…