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NEJM — Recent Cardiology Articles- Science behind the Study: Remuscularizing the Failing Human Heart May 28, 2026The author describes the scientific foundations of a phase 1–2 study of stem-cell–derived ventricular assist tissue transplanted onto the epicardial surface of failing human hearts.
- Advanced Therapy for Intermediate-Risk Pulmonary Embolism May 28, 2026Pulmonary embolism is the third leading cardiovascular cause of complications and death after myocardial infarction and stroke, with a rising incidence globally.1 The approach to management of acute pulmonary embolism as a condition to be treated nonsurgically with systemic heparin anticoagulation was established more than 60 years ago.
- Patching Up Damaged Hearts May 28, 2026Heart failure resulting from previous myocardial infarction or ischemic cardiomyopathy remains a leading cause of death and complications worldwide. The central pathophysiological processes in ischemic cardiomyopathy are the loss of myocardial tissue from necrosis after a coronary-artery occlusion, followed by replacement fibrosis that confers a disposition to heart failure and...
- Cutting to the Chase May 28, 2026This interactive feature describes a 71-year-old woman with a history of type 2 diabetes, heart failure with a reduced ejection fraction, and stage 3 CKD who presented to the ED with worsening pain in her left buttock that had begun 1 week earlier. Test your diagnostic and therapeutic skills at...
- Double Take: Cardiovascular Risk Factors — Hypertension May 28, 2026This Double Take video outlines the five risk factors for cardiovascular disease and reviews strategies for blood-pressure control to reduce morbidity and mortality.
- Science behind the Study: Remuscularizing the Failing Human Heart May 28, 2026