June 18th, 2012
The Grim Impact of Loneliness and Living Alone
Larry Husten, PHD
Two new reports published in the Archives of Internal Medicine throw a spotlight on the grim effects of loneliness and living alone on health.
As part of the Health and Retirement Study, 1604 people were followed for 6 years after answering a questionnaire about loneliness. Some 43% reported feeling lonely. Loneliness was associated with significantly increased risks for death and other adverse outcomes:
- Death: 22.8% vs. 14.2%, adjusted risk ratio (RR) 1.45, CI 1.11-1.88
- Decline in activities of daily living: 24.8% vs. 12.5%, RR 1.59, CI 1.23-2.07
- Difficulty with upper extremity tasks: 41.5% vs. 28.3%, RR 1.28, CI 1.08- 1.52
- Decline in mobility: 38.1% vs. 29.4%, RR 1.18, CI 0.99-1.41
- Difficulty with climbing: 40.8% vs. 27.9%, RR 1.31, CI 1.10-1.57
The authors of the study recommend that physicians ask their patients about loneliness so that they “will be better able to target interventions intended to prevent functional decline and disability.”
In the second study, investigators from the REduction of Atherothrombosis for Continued Health (REACH) Registry analyzed data from 44,573 individuals, 8594 of whom were living alone. This group had significantly higher risks for death and cardiovascular death than those not living alone (p<0.01):
- 4-year mortality: 14.1% vs. 11.1%
- CV death: 8.6% vs. 6.8%
In an invited commentary, Emily Bucholz and Harlan Krumholz (who is also editor-in-chief of CardioExchange) discuss the myriad difficulties and complexities involved in understanding and employing social support. Scientists, they write, should be “challenged to investigate mechanisms as well as practical interventions that can be used to address the social factors that undermine health.”
Categories: General, Prevention
Tags: geriatrics, loneliness, social support
You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.
3 Responses to “The Grim Impact of Loneliness and Living Alone”
Search the Archive
Archives by Date
NEJM — Recent Cardiology Articles- Digital Twin–Guided Ablation for Ventricular Tachycardia April 2, 2026In a 10-patient feasibility study, heart digital twins were used to guide VT ablation. Afterward, VT was noninducible in all patients; at a mean follow-up of 13 months, 8 patients were free of recurrence, without drug therapy.
- Discontinuation of Beta-Blocker Therapy after Myocardial Infarction April 2, 2026Among patients with a preserved ejection fraction at least 1 year after myocardial infarction, stopping beta-blockers was noninferior to continuing therapy with respect to major clinical outcomes.
- Simulating and Teaching the Physiology of Pulsus Paradoxus April 2, 2026In a simulation involving 15 healthy trainees, slowing respiration to 10 seconds per breath produced pulsus measurements exceeding 20 mm Hg, enabling improved teaching simulation and understanding of underlying physiology.
- The Age Illusion — Limitations of Chronologic Age in Medicine April 2, 2026Chronologic age plays an outsized role in various aspects of medicine. Yet people of the same age can differ dramatically when it comes to aging-related risk factors.
- Left Atrial Appendage Closure — Another Overused Method in Cardiology? April 2, 2026Untreated atrial fibrillation carries an approximately 3 to 5% annual risk of ischemic stroke. Long-term oral anticoagulation therapy decreases this risk to 1.7% with warfarin and to 1.5% with edoxaban, as shown in the ENGAGE AF-TIMI 48 (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction...
- Digital Twin–Guided Ablation for Ventricular Tachycardia April 2, 2026
-
Tag Cloud
- ACS AF AHA anticoagulation aortic valve replacement apixaban aspirin atrial fibrillation CABG cardiovascular risk cholesterol clopidogrel dabigatran diabetes diet drug-eluting stents epidemiology ESC exercise FDA FDA approvals Fellowship training guidelines HDL heart failure hypertension ICDs MI myocardial infarction obesity PCI Primary PCI risk factors rivaroxaban statins STEMI stents stroke stroke prevention TAVI TAVR type 2 diabetes venous thromboembolism warfarin women

As a geriatrician I am trying to understand the benefits of community living.
Unless they have a significant allergy, a pet is an excellent way to mitigate the feeling of loneliness. A puppy or kitten can work wonders.
I’ve written prescriptions for shelter dogs/cats. Sometimes puppies and kittens are too much for elderly. Older animals who have been neglected, mistreated or unappreciated in their lives offer a ‘mutual bond’, if you will, kind of a commiseration. It seems to be a win-win unity. My little rat terrier/beagle mix was mistreated and obviously abused by her former owner and discarded/abandoned when pregnant. Best dog I’ve ever had. BFF&E! Just wish our lifespans were similar; but this gap is narrowed with the elderly.