CardioExchange, an NEJM practice community for medical professionals dedicated to improving cardiac patient care, was active from 2009 to 2015. CardioExchange fostered discussion between clinicians from across the globe.
The author describes the scientific foundations of a phase 1–2 study of stem-cell–derived ventricular assist tissue transplanted onto the epicardial surface of failing human hearts.
Pulmonary embolism is the third leading cardiovascular cause of complications and death after myocardial infarction and stroke, with a rising incidence globally.1 The approach to management of acute pulmonary embolism as a condition to be treated nonsurgically with systemic heparin anticoagulation was established more than 60 years ago.
Heart failure resulting from previous myocardial infarction or ischemic cardiomyopathy remains a leading cause of death and complications worldwide. The central pathophysiological processes in ischemic cardiomyopathy are the loss of myocardial tissue from necrosis after a coronary-artery occlusion, followed by replacement fibrosis that confers a disposition to heart failure and...
This interactive feature describes a 71-year-old woman with a history of type 2 diabetes, heart failure with a reduced ejection fraction, and stage 3 CKD who presented to the ED with worsening pain in her left buttock that had begun 1 week earlier. Test your diagnostic and therapeutic skills at...
This Double Take video outlines the five risk factors for cardiovascular disease and reviews strategies for blood-pressure control to reduce morbidity and mortality.