CardioExchange, an NEJM practice community for medical professionals dedicated to improving cardiac patient care, was active from 2009 to 2015. CardioExchange fostered discussion between clinicians from across the globe.
The management of carotid-artery stenosis that has not caused recent symptoms — asymptomatic carotid stenosis — has been controversial. Clinical trials that began more than 30 years ago showed a small benefit of carotid endarterectomy as compared with medical treatment, but improvements in medical prevention of stroke call into question...
Sudden cardiac arrest in athletes may be attributable to cardiac and noncardiac causes. With diagnosis and treatment, a return to play may be reasonable. Prevention, emergency planning, and shared decision making are key.
In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit.
More than 470,000 patients with kidney failure receive hemodialysis in the United States alone, with worldwide estimates approaching 3 million patients. Mortality from kidney failure remains unacceptably high, with recent U.S. estimates of approximately 18% per year — higher than the mortality observed among patients with heart failure, diabetes, or...
In the 16th century, the Flemish physician and anatomist Andreas Vesalius fundamentally advanced our understanding of the structure and function of the human body, providing particular insight on the inner workings of the circulatory system.1 The results of the VESALIUS-CV (Effect of Evolocumab in Patients at High Cardiovascular...