An ongoing dialogue on HIV/AIDS, infectious diseases,
May 25th, 2023
The Legacy of a Disappointing HIV Clinical Trial — Does It Still Apply to HIV Today?
A long, long time ago, back in the early exciting days of raltegravir, the first HIV integrase inhibitor, we learned something important from a clinical trial with disappointing results. The trial bore the (barely) hidden name of the company that developed the drug — SWITCHMRK, get it? — and had a profound impact on how […]
May 15th, 2023
Types of HIV Papers — A Quick Guide
I spend a lot of my time reading HIV clinical research papers. A lot. So here, for your viewing pleasure, is a poster I updated and modified from a brilliant xkcd web comic (using this tool), describing some common HIV clinical research themes. Suitable for framing, it should prove helpful as you embark on your […]
May 8th, 2023
As the Public Health Emergency Comes to an End, How Are We Feeling About This?
As you no doubt heard, on Friday, May 5, 2023, the WHO declared the end of the global health emergency from COVID-19. Here in the U.S., the federal public health emergency will expire on May 11. That’s Thursday, just a few days from now. These events reflect two realities that, while seemingly contradictory, make these […]
Paul E. Sax, MD
Associate Editor
NEJM Clinician
Biography | Disclosures & Summaries
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