Archive for July, 2015

July 26th, 2015

Really Rapid Review — IAS 2015, Vancouver

Vancouver will always have a special place in HIV treatment history. It was here, in 1996, that many of us first saw the potential of combination antiretroviral therapy to control this disease. Specifically, Study 035 of AZT, 3TC, and indinavir (presented by Trip Gulick) demonstrated the astounding finding that triple therapy induced sustained virologic suppression and dramatic immunologic improvement. Could it be that […]


July 18th, 2015

Disrupting the Normal Microbiota Might Make Us Fat, Allergic, Asthmatic, and Lead to Celiac Disease

Over at Open Forum Infectious Diseases, I recently had the opportunity to interview Dr. Martin Blaser, Professor of Medicine and Microbiology at New York University. He’s also the Director of the Human Microbiome Project, and author of the book, Missing Microbes: How the overuse of antibiotics is fueling our modern plagues. Marty has been a long-time champion […]


July 11th, 2015

Citing WHO Guidelines, Squirrels Protest Latest Virus Discovery

An open letter to the Editor-in-Chief of the New England Journal of Medicine Saturday, July 11, 2015 Dear Dr. Drazen: On behalf of the International Association of Variegated Squirrels, I am writing to protest the article that appeared in your July 9 2015 issue, entitled “A variegated squirrel bornavirus associated with fatal human encephalitis.”  We […]


July 7th, 2015

For HIV in the USA, Not in Care Exceeds the Undiagnosed — Solutions Welcome

In last week’s post, I asked about two of the key components of the HIV care cascade — the “undiagnosed” vs the “diagnosed but not in care,” and which group was larger in the USA. Here are your answers as of now: The people who read this site are a pretty knowledgeable group when it comes […]


July 1st, 2015

Undiagnosed or Not in Care? For HIV, Which Is the Bigger Problem?

These days, it’s hard to have a “closed book” examination. The information is everywhere — on your computer, your phone, your tablet — whatever screen happens to be glowing in front of you. “In the age of the internet, why be wrong?” is something my son used to say as we sat at the dinner table, […]


HIV Information: Author Paul Sax, M.D.

Paul E. Sax, MD

Associate Editor

NEJM Clinician

Biography | Disclosures & Summaries

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