January 31st, 2014
A (Not So) New Drug Landscape for Pulmonary Arterial Hypertension
John Ryan, MD
John Ryan offers a primer on three newly approved drugs for pulmonary arterial hypertension.
January 31st, 2014
American College of Cardiology Announces Late-Breaking Clinical Trials
Larry Husten, PHD
The American College of Cardiology announced the lineup of late-breaking clinical trials for its upcoming annual meeting in Washington, DC. The opening session will include the most eagerly anticipated trials — the main results of Symplicity HTN-3 and the comparison of Corevalve and surgery in high-risk patients. Subsequent sessions will include several phase-3 trials of PCSK9 inhibitors. Here […]
January 30th, 2014
Johnson & Johnson Will Share Clinical Trial Data
Larry Husten, PHD
In a major victory for advocates of open access to data from clinical trials, Johnson & Johnson today announced that it will make all of its clinical trial data available to outside researchers. The company said that the Yale University Open Data Access (YODA) Project will serve as an independent third party “to review requests […]
January 30th, 2014
To Merge or Not to Merge: Physician Professional and Personal Identities on Social Media
Vineet Arora, MD, MAPP
Vineet Arora shares her expertise in developing a balance between your professional and private identities on social media.
January 30th, 2014
Selections from Richard Lehman’s Literature Review: January 30th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include articles on the FDA’s premarket approval of cardiac implantable electronic devices, the Stryker Wingspan stent system, and more.
January 29th, 2014
What’s the Best Blood Transfusion Protocol for Anemic ACS Patients?
Sunil Rao, MD
Sunil V. Rao discusses his editorial about TRANSFUSION-2, a study of the platelet and inflammatory effects of blood transfusions in ACS and non-ACS patients with anemia.
January 28th, 2014
Problems Persist Despite Gains in Oral Anticoagulant Use
Larry Husten, PHD
Although significant progress has been made in recent years, a new survey from the European Society of Cardiology finds that there are still too many atrial fibrillation patients who are not taking the best medications to reduce their elevated risk for stroke. Many elderly patients are not receiving oral anticoagulants — either traditional warfarin or […]
January 28th, 2014
Cholesterol Guidelines: Annals of Internal Medicine Offers a Guide for the Perplexed
The guidelines on assessing cardiovascular risk and cholesterol levels that were released in November have not had a calming effect on clinicians, according to commentators. The Annals of Internal Medicine offers four articles meant to allay fears — or at least provide some perspective. The articles include a synopsis of the guidelines. Skeptical commentators argue […]
January 27th, 2014
USPSTF Issues Draft Recommendations on Abdominal Aortic Aneurysm Screening
Nicholas Downing, MD
The U.S. Preventive Services Task Force now says that the evidence is insufficient to weigh the benefits and harms of screening for abdominal aortic aneurysm (AAA) in women aged 65 to 75 who’ve ever smoked. In its previous 2005 guideline the USPFSTF clearly advised against screening for all women. An updated review by the Task […]
January 27th, 2014
Prevention Guidelines in Practice: Vignette 3
Siqin Ye, MD
Tell us how you’d determine this 41-year-old African American woman’s 10-year CVD risk, and if you’d put her on a statin.