January 6th, 2014
Selections from Richard Lehman’s Literature Review: January 6th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the NAVIGATOR study, trials of stents, mitral valve repair vs. replacement, and more.
NEJM — Recent Cardiology Articles- Endovascular Therapy for Medium-Vessel Occlusion Stroke — Narrowing the Target Population May 14, 2026One way to classify acute ischemic stroke is by the anatomy of vessel occlusion. Initial randomized trials of endovascular thrombectomy focused on large-vessel occlusions.1-5 These proximal occlusions of the intracranial carotid artery or the stem of the middle cerebral artery (MCA) represent the most severe form of anterior...
- Central Retinal-Vein Occlusion May 14, 2026A 65-year-old woman with cardiovascular risk factors presented with a 14-hour history of painless, worsening, blurry vision in the right eye (visual acuity, 20/400). Funduscopy showed diffuse retinal hemorrhages and venous dilatation.
- Endovascular Treatment of Medium-Vessel-Occlusion Strokes May 14, 2026Among patients with stroke due to medium-vessel occlusion, thrombectomy led to functional independence at 90 days (in 58.6% of patients, vs. 46.6% with medical management) but also to a higher risk of intracranial hemorrhage.
- Double Take: HFpEF Explained — Living with HFpEF May 7, 2026This patient-focused Double Take video describes heart failure with preserved ejection fraction and how it is managed.
- Price of Protection — Microaxial Flow Pump in High-Risk PCI May 7, 2026In the catheterization laboratory, the most consequential decisions are frequently not about whether to treat, but rather about how far to extend treatment. Nowhere is that tension more apparent than in high-risk percutaneous coronary intervention (PCI). In these cases, the margin between a good outcome and a catastrophic one is...
- Endovascular Therapy for Medium-Vessel Occlusion Stroke — Narrowing the Target Population May 14, 2026