January 6th, 2014
Selections from Richard Lehman’s Literature Review: January 6th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the NAVIGATOR study, trials of stents, mitral valve repair vs. replacement, and more.
NEJM — Recent Cardiology Articles- Digital Twin–Guided Ablation for Ventricular Tachycardia April 2, 2026In a 10-patient feasibility study, heart digital twins were used to guide VT ablation. Afterward, VT was noninducible in all patients; at a mean follow-up of 13 months, 8 patients were free of recurrence, without drug therapy.
- Discontinuation of Beta-Blocker Therapy after Myocardial Infarction April 2, 2026Among patients with a preserved ejection fraction at least 1 year after myocardial infarction, stopping beta-blockers was noninferior to continuing therapy with respect to major clinical outcomes.
- Simulating and Teaching the Physiology of Pulsus Paradoxus April 2, 2026In a simulation involving 15 healthy trainees, slowing respiration to 10 seconds per breath produced pulsus measurements exceeding 20 mm Hg, enabling improved teaching simulation and understanding of underlying physiology.
- The Age Illusion — Limitations of Chronologic Age in Medicine April 2, 2026Chronologic age plays an outsized role in various aspects of medicine. Yet people of the same age can differ dramatically when it comes to aging-related risk factors.
- Left Atrial Appendage Closure — Another Overused Method in Cardiology? April 2, 2026Untreated atrial fibrillation carries an approximately 3 to 5% annual risk of ischemic stroke. Long-term oral anticoagulation therapy decreases this risk to 1.7% with warfarin and to 1.5% with edoxaban, as shown in the ENGAGE AF-TIMI 48 (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction...
- Digital Twin–Guided Ablation for Ventricular Tachycardia April 2, 2026