An ongoing dialogue on HIV/AIDS, infectious diseases,
Paul E. Sax, MD
Associate Editor
NEJM Clinician
Biography | Disclosures & Summaries
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FROM NEJM — Recent Infectious Disease Articles- Shock Not Advised April 25, 2026A physician offers to help in a medical emergency on a transatlantic flight. Though she faces limits of bureaucracy, equipment, and ultimately biology, she discovers her physicianhood is inescapable.
- Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock April 24, 2026In children with septic shock, no significant difference was seen in the incidence of death, new renal-replacement therapy, or persistent kidney dysfunction with balanced fluid as compared with 0.9% saline for fluid resuscitation.
- Tuberculosis Cases and Deaths Averted by PEPFAR April 23, 2026Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR program on incident cases of tuberculosis and related deaths is presented.
- Case 12-2026: An 86-Year-Old Woman with Anorexia, Weight Loss, and Liver Lesions April 23, 2026An 86-year-old woman with a history of diabetes and breast cancer was admitted to the hospital with anorexia and weight loss. Imaging revealed multifocal liver lesions. A diagnosis was made.
- Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir April 23, 2026The first cases of Covid-19 were reported at the end of 2019, and from January 20, 2020, to May 5, 2023, Covid-19 was considered to be a public health emergency of international concern. The total number of cases worldwide exceeded 1 million by early April 2020. In the United States,...
- Shock Not Advised April 25, 2026